[HTML][HTML] … failure associated with cytochrome b codon 268 mutation during treatment of falciparum malaria with atovaquone–proguanil in traveller returning from Congo

…, R Amalvict, P Delaunay, J Mosnier, P Marty… - Malaria Journal, 2020 - Springer
… multiple mutations in the Plasmodium falciparum dihydrofolate reductase (… This is the first
report of genetic confirmation of atovaquone–proguanil … falciparum isolate acquired in Congo. …

[HTML][HTML] A case report of late treatment failure in Plasmodium falciparum malaria in a traveler from the Democratic Republic of the Congo to India

S Sharma, N Ahmed, N Faizi, PK Bharti, A Sharma… - IDCases, 2023 - Elsevier
falciparum (confirmed genetically) malaria with 3% parasitemia after one week of complete
treatment was reported in a non-immune traveler to East Africa [12]. In non-immune travelers

Mitochondrial heteroplasmy is responsible for Atovaquone drug resistance in Plasmodium falciparum

S Siegel, A Rivero, SR Adapa, CQ Wang, R Manetsch… - BioRxiv, 2017 - biorxiv.org
Genetic Confirmation of Atovaquone-Proguanil-Resistant Plasmodium falciparum Malaria
Acquired by a Nonimmune Traveler to East Africa. Clinical Infectious Diseases 37, 450–451, …

Within-host selection of drug resistance in a mouse model of repeated incomplete malaria treatment: comparison between atovaquone and pyrimethamine

S Nuralitha, JE Siregar, D Syafruddin… - Antimicrobial Agents …, 2016 - Am Soc Microbiol
… with genetic lesions in the dihydrofolate reductase gene in … Drug-resistant Plasmodium
falciparum organisms have been … The manifestation of such acquired immunity to P. berghei, …

Advanced molecular detection of malarone resistance

E Talundzic, MM Plucinski, S Biliya… - Antimicrobial Agents …, 2016 - Am Soc Microbiol
… of travel to Nigeria was diagnosed with uncomplicated Plasmodium falciparum malaria by
… Sanger sequencing of the cytochrome b gene, encoding the molecular target of atovaquone…

[HTML][HTML] Molecular Surveillance for Imported Antimicrobial Resistant Plasmodium falciparum, Ontario, Canada

R Kariyawasam, R Lau, E Shao, K Tan… - Emerging Infectious …, 2022 - ncbi.nlm.nih.gov
… the copy number of multidrug resistance genes (pfmdr1) in P. … returning from Kenya, Angola,
and many parts of East Africa (… of complete data on travel history, history of malaria infection, …

Preventing Mosquito Bites With Personal Protection Measures

H Chloroquine - Travel Medicine E-Book, 2018 - books.google.com
Genetic confirmation of atovaquone-proguanil resistant Plasmodium falciparum malaria
acquired by a nonimmune traveler to East Africa. Clin Infect Dis 2003; 37: 450–1. …

An overview of currently available antimalarials

N Yu Gorobets, YV Sedash, BK Singh… - Current topics in …, 2017 - ingentaconnect.com
… clinical data that hopefully will be gained in the post-licensure … , the first report on
atovaquone-proguanil resistant malaria has ap… in G6PD, a genetic polymorphism with a …

[HTML][HTML] Decoding the Molecular Effects of Atovaquone Linked Resistant Mutations on Plasmodium falciparum Cytb-ISP Complex in the Phospholipid Bilayer …

L Chebon-Bore, TA Sanyanga, CV Manyumwa… - International Journal of …, 2021 - mdpi.com
… , there are two interactions that were gained in the Y268C and Y268S mutant systems. These
… study findings focusing on the local residue level confirm the effect of mutations on protein …

Combating antimicrobial resistance in malaria, HIV and tuberculosis

M Duffey, RW Shafer, J Timm, JN Burrows… - Nature Reviews Drug …, 2024 - nature.com
Plasmodium falciparum, Plasmodium vivax and Plasmodium … Although direct causality has
been confirmed by allelic … frequency and genetic mechanisms of transmitted and acquired HIV …